
PARADISe is a software program for resolving untargeted Gas Chromatography Masss Spectromety (GC-MS) data. This page contains a description of the software and the official versions available for downloading, starting from PARADISe version 6.
With PARADISe you can import .CDF data files which most instruments can export to. Alternatively, you can import MATLAB formatted data from so-called mat-files if relevant. A template for how to structure the mat-file is bundled as part of the installation.
Once data have been imported, you define retention time intervals which contain chemical peaks and PARADISe will then resolve and separate signals, such that the spectrum and peak area (relative concentration) are purified from baseline and overlapping/coeluting compounds. PARADISe will output a peak table, in excel format, containing the peak area and the purified spectrum for each resolved compound. A more detailed guideline is provided in the program under the welcome tab.
If you have NIST MSSEARCH, PARADISe also includes the best matches based on your NIST MSSEARCH settings.
The official version is an executable (*.exe) for Windows 10/11, but you can also download the software as a MATLAB app for use in MATLAB version 2022a.

Get the latest stable version 6.0.1 here:
- PARADISe for Windows version (with MATLAB runtime)
- If you are more adventurous, you can download PARADISe (without MATLAB runtime). Note that it will only work with the runtime from MATLAB version 2022a.
- You can also get PARADISe as a MATLAB app. But it will only work for MATLAB version 2022a or later and you will need the deep learning toolbox (download)
If you are using PARADISe for scientific publications, we encourage you to reference this page and specify the version used, as well as the paper:
Beatriz Quintanilla-Casas, Rasmus Bro, Jesper Løve Hinrich et al. Tutorial on PARADISe: PARAFAC2-based Deconvolution and Identification System for processing GC–MS data, 19 January 2023, PROTOCOL (Version 1) available at Protocol Exchange [https://doi.org/10.21203/rs.3.pex-2143/v1]
Resources and help
You can find the PARADISe discussion board here where you can post comments and questions.
We have a tutorial on how to use the software. Tip: go to Supplementary for a better typeset version
See a video introduction to PARADISe
The history of PARADISe as seen through papers
